CINV  

Talking with your doctor about EMEND

There is help for chemotherapy-induced nausea and vomiting (CINV)

Nausea and vomiting can be common side effects during some types of chemotherapy.

Illustration about a study on nausea and vomiting from chemotherapy In a study where all patients received commonly prescribed preventive medicines for nausea and vomiting, but did not receive EMEND almost half (48%) still had nausea and vomiting from chemotherapy.*

*In this study, medicines included a 5-HT3 antagonist (ondansetron) and a corticosteroid (dexamethasone). Patients received chemotherapy associated with a high risk of nausea and vomiting.

Ask your health care team about EMEND

Help stop CINV before it starts. Ask your health care team about EMEND. Here are a few questions to help you get the conversation started.

  • What is EMEND?
  • Is EMEND right for me?
  • How does EMEND work differently from other medicines to prevent CINV?

EMEND is used in adults to prevent nausea and vomiting caused by certain anticancer medicines. EMEND is always used with other medicines.

EMEND is not used to treat nausea and vomiting that you already have.

EMEND should not be used continuously for a long time (chronic use).

Important Safety Information

  • Do not take EMEND® (aprepitant) if you are taking Orap (pimozide), Seldane (terfenadine), Hismanal (astemizole), or Propulsid (cisapride). Taking EMEND with any of these medicines could cause serious or life-threatening problems. Do not take EMEND if you are allergic to any of the ingredients in EMEND.
  • Before you take EMEND, tell your doctor if you have liver problems.
  • Before you take EMEND, tell your doctor if you are pregnant or plan to become pregnant because it is not known if EMEND can harm your unborn baby. Women who use birth control medicines containing hormones (birth control pills, skin patches, implants, and certain IUDs) should also use a backup method of birth control to prevent pregnancy during treatment with EMEND and for up to 1 month after using EMEND.
  • Before you take EMEND, tell your doctor if you are breast-feeding because it is not known if EMEND passes into your milk and if it can harm your baby.
  • EMEND may affect how other medicines work, including chemotherapy. Other medicines may affect how EMEND works. Tell your doctor about all the medicines you are taking or plan to take, including prescription or nonprescription medicines, vitamins, or herbal supplements.
  • If you take the blood-thinner medicine warfarin sodium (Coumadin or Jantoven), your doctor may do blood tests after you take EMEND to check your blood clotting.
  • EMEND may cause serious side effects, including serious allergic reactions such as hives, rash, itching, and trouble breathing or swallowing. Severe skin reactions may occur rarely. Stop taking EMEND and call your doctor right away if you have any of these signs or symptoms of an allergic reaction.
  • The most common side effects of EMEND are tiredness, nausea, hiccups, constipation, diarrhea, loss of appetite, headache, and hair loss. These are not all the possible side effects of EMEND.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

EMEND is available by prescription only. Please read the Patient Information for EMEND and discuss it with your doctor. The physician Prescribing Information also is available.