Despite treatment with a 5-HT3 receptor antagonist and a corticosteroid,
nausea & vomiting remains a serious problem.
Results from clinical trials show patients still suffer from chemotherapy-induced nausea and vomiting (CINV).
- Reference:1.Warr DG, Hesketh PJ, Gralla RJ, et al. Efficacy and tolerability of aprepitant for the prevention of chemotherapy-induced nausea and vomiting in patients with breast cancer after moderately emetogenic chemotherapy. J Clin Oncol. 2005;23(12):2822–2830.
