Chemo-Induced Nausea and Vomiting I.V. Medication: Dosing and administration information
Merck

3 days of dosing are required

  • For patients at risk of CINV due to HEC or MEC, EMEND always should be taken on Days 1, 2, and 3 of each cycle, in combination with a 5-HT3 receptor antagonist and a corticosteroid, even if patients do not experience nausea and vomiting on Day 1.
  • All 3 doses of EMEND are required for the full 5 days of CINV protection.

Realize the full benefit

Talk with your patients

  • Explain the importance of taking EMEND on Days 2 and 3 of every cycle, even if patients do not experience nausea and vomiting on Day 1.
  • Remember that the ACT Program is available to provide assistance to qualified patients.
  • Ensure that managed care and Medicare patients know that EMEND usually is covered:

    EMEND has favorable formulary status

    • 96% of patients with managed care plans have EMEND on Tier 2 or Tier 3.
    • 100% of patients with Medicare Part D plans have EMEND on Tier 2 or Tier 3.
    Copayments may be affordable for your patients
Common Copayments for EMEND
  Plan Coverage for EMEND National Copayment
Managed care plans Tier 2 status for 73% of covered lives $241
Tier 3 status for 23% of covered lives $451
Medicare Part D plans Tier 2 status for 75% of covered lives $301,a
Tier 3 status for 25% of covered lives $601,a

aThe table shows the most common copayment amount as the mode, not the average, for Medicare products.

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Important Safety Information

EMEND and EMEND for Injection, in combination with other antiemetic agents, are indicated in adults for prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy, including high-dose cisplatin.

EMEND and EMEND for Injection have not been studied for treatment of established nausea and vomiting. Chronic continuous administration of EMEND or EMEND for Injection is not recommended.

Selected Important Safety Information

Before prescribing EMEND or EMEND for Injection, please read the Prescribing Information. The Patient Information also is available.

The information on this site is intended for health care professionals in the United States and is not intended for the general public.

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